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Missing the point: Non-convergence in iterative imputation algorithms

Iterative imputation is a popular tool to accommodate missing data. While it is widely accepted that valid inferences can be obtained with this technique, these inferences all rely on algorithmic convergence. There is no consensus on how to evaluate …

Patient and anesthesia characteristics of children with low pre‐incision blood pressure: A retrospective observational study

Background: Intraoperative blood pressure has been suggested as a key factor for safe pediatric anesthesia. However, there is not much insight into factors that discriminate between children with low and normal pre‐incision blood pressure. Our aim …

The Global Scale for Early Development (GSED)

Critically, each of these investments requires that governments and stakeholders implement metrics to track their progress in achieving ECD-related targets and goals. National and global measurement of progress is of critical importance for ensuring …

Multiple imputation in data that grow over time: A comparison of three strategies

Multiple imputation is a highly recommended technique to deal with missing data, but the application to longitudinal datasets can be done in multiple ways. When a new wave of longitudinal data arrives, we can treat the combined data of multiple waves …

Flexible Imputation of Missing Data. Second Edition

Missing data pose challenges to real-life data analysis. Simple ad-hoc fixes, like deletion or mean imputation, only work under highly restrictive conditions, which are often not met in practice. Multiple imputation replaces each missing value by …

Combining multiple imputation and bootstrap in the analysis of cost-effectiveness trial data

In healthcare cost‐effectiveness analysis, probability distributions are typically skewed and missing data are frequent. Bootstrap and multiple imputation are well‐established resampling methods for handling skewed and missing data. However, it is …

Multiple imputation for multilevel data with continuous and binary variables

We present and compare multiple imputation methods for multilevel continuous and binary data where variables are systematically and sporadically missing. The methods are compared from a theoretical point of view and through an extensive simulation …

Multiple imputation of multilevel data

This chapter discusses critical issues associated with imputation of multilevel data. Section 10.2 introduces the notation used and outlines how two formulations of the same model are related. Section 10.3 dissects the multilevel missing data problem …