This paper outlines a strategy to validate multiple imputation methods. Rubin’s criteria for proper multiple imputation are the point of departure. We describe a simulation method that yields insight into various aspects of bias and efficiency of the …
**Objective**: To determine whether the inverse relation between blood pressure and all cause mortality in elderly people over 85 years of age can be explained by adjusting for health status, and to determine whether high blood pressure is a risk …
This paper deals with problems concerning missing data in clinical databases. After signalling some shortcomings of popular solutions to incomplete data problems, we outline the concepts behind multiple imputation. Multiple imputation is a …
This paper deals with problems concerning missing data in statistical databases. Multiple imputation is a statistically sound technique for handling incomplete data. Two problems should be addressed before the routine application of the technique …