Background: From 2002, TNO developed a list of 60 potential relevant determinants of innovation implementation. These factors were based is a review of empirical studies, Delphi studies among experts and some original empirical studies in the Netherlands. Methods: Meta-analyses of 8 empirical studies on the implementation of preventive innovations in Dutch youth health care and schools. Each study was based in the initial framework of 60 determinants. Data were combined into one set. Missings were replaced by plausible values using multiple imputation. Reduction …